Ultrasound Imaging Review

How valuable is ultrasound imaging in assessing hemophilic arthropathy in children and adults?

ASH 2015 (Orlando, December 5-8) A study was conducted to evaluate the evidence on the value of ultrasound (US) for the assessment of hemophilic arthropathy, or joint disease, in children and adults with hemophilia. The goal of the study was to answer the following questions: 1) Are currently available ultrasound methods accurate for early diagnosis of joint disease findings? 2) Can prophylaxis treatment with factor reduce the incidence of ultrasound-detectable findings in of joint disease? 3) Do ultrasound scores correlate with clinical and other x-ray or MRI findings in the evaluation of joint disease? 4) Are ultrasound findings correlated with how the joints are currently functioning?

According to data presented at the American Society of Hematology (ASH) 2015 Annual Meeting, the study found that there is insufficient evidence at the present time to recommend ultrasound as an accurate method for early diagnosis, to demonstrate that US scores correlate with clinical and other x-ray or MRI findings, that treatment can reduce the incidence of US-detectable findings of joint disease in patients with hemophilia, or to prove an association between ultrasound findings and the way the joints are currently functioning. The results suggest additional research studies are needed to determine the value of US as a tool for early diagnosis of joint disease in children and adults.